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Crystal Structure of Staphylococcus aureus Metallopeptidase (Sapep) Reveals Large Domain Motions between the Manganese-bound and Apo-states

Proteases belonging to the M20 family are characterized by diverse substrate specificity and participate in several metabolic pathways. The Staphylococcus aureus metallopeptidase, Sapep, is a member of the aminoacylase-I/M20 protein family. This protein is a Mn(2+)-dependent dipeptidase. The crystal...

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Detalhes bibliográficos
Main Authors: Girish, Tavarekere S., Gopal, Balasubramanian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937973/
https://ncbi.nlm.nih.gov/pubmed/20610394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.147579
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