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Toxoplasma Rhoptry Protein 16 (ROP16) Subverts Host Function by Direct Tyrosine Phosphorylation of STAT6

The obligate intracellular parasite, Toxoplasma gondii, modulates host immunity in a variety of highly specific ways. Previous work revealed a polymorphic, injected parasite factor, ROP16, to be a key virulence determinant and regulator of host cell transcription. These properties were shown to be p...

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Autors principals: Ong, Yi-Ching, Reese, Michael L., Boothroyd, John C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937901/
https://ncbi.nlm.nih.gov/pubmed/20624917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.112359
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