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Evidence for Avian and Human Host Cell Factors That Affect the Activity of Influenza Virus Polymerase

Typical avian influenza A viruses do not replicate efficiently in humans. The molecular basis of host range restriction and adaptation of avian influenza A viruses to a new host species is still not completely understood. Genetic determinants of host range adaptation have been found on the polymeras...

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Autors principals: Moncorgé, Olivier, Mura, Manuela, Barclay, Wendy S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937815/
https://ncbi.nlm.nih.gov/pubmed/20631125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01134-10
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