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Elucidating the Interactions between Influenza Virus Polymerase and Host Factor ANP32A

The avian-origin influenza A virus polymerase is restricted in human cells. This restriction has been associated with species differences in host factor ANP32A. Avian ANP32A supports the activity of an avian-origin polymerase. However, the avian-origin polymerase is incompatible with human ANP32A. A...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Mistry, Bhakti, Long, Jason S., Schreyer, Jocelyn, Staller, Ecco, Sanchez-David, Raul Yusef, Barclay, Wendy S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000967/
https://ncbi.nlm.nih.gov/pubmed/31694956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01353-19
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