A New Cistron in the Murine Hepatitis Virus Replicase Gene

We report an RNA-negative, temperature-sensitive (ts) mutant of Murine hepatitis virus, Bristol ts31 (MHV-Brts31), that defines a new complementation group within the MHV replicase gene locus. MHV-Brts31 has near-normal levels of RNA synthesis at the permissive temperature of 33°C but is unable to s...

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Bibliographische Detailangaben
Hauptverfasser: Stokes, Helen L., Baliji, Surendranath, Hui, Chang Guo, Sawicki, Stanley G., Baker, Susan C., Siddell, Stuart G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Genome Replication and Regulation of Viral Gene Expression
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937787/
https://ncbi.nlm.nih.gov/pubmed/20668085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00901-10
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