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Characterization of the Alpha Interferon-Induced Postentry Block to HIV-1 Infection in Primary Human Macrophages and T Cells

Type I interferon (IFN) inhibits virus replication by activating multiple antiviral mechanisms and pathways. It has long been recognized that alpha interferon (IFN-α) can potently block both early and late stages of HIV-1 replication. The mechanistic basis for the early block(s) to infection is unkn...

詳細記述

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書誌詳細
主要な著者: Goujon, Caroline, Malim, Michael H.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937661/
https://ncbi.nlm.nih.gov/pubmed/20610724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00854-10
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