Replication of Subgenomic Hepatitis C Virus Replicons in Mouse Fibroblasts Is Facilitated by Deletion of Interferon Regulatory Factor 3 and Expression of Liver-Specific MicroRNA 122

Hepatitis C virus (HCV) infection causes significant morbidity, and efficient mouse models would greatly facilitate virus studies and the development of effective vaccines and new therapeutic agents. Entry factors, innate immunity, and host factors needed for viral replication represent the initial...

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Autori principali: Lin, Liang-Tzung, Noyce, Ryan S., Pham, Tram N. Q., Wilson, Joyce A., Sisson, Gary R., Michalak, Thomas I., Mossman, Karen L., Richardson, Christopher D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937658/
https://ncbi.nlm.nih.gov/pubmed/20592082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00559-10
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