Establishment of a Subgenomic Replicon for Bovine Viral Diarrhea Virus in Huh-7 Cells and Modulation of Interferon-Regulated Factor 3-Mediated Antiviral Response

We describe the development of a selectable, bi-cistronic subgenomic replicon for bovine viral diarrhea virus (BVDV) in Huh-7 cells, similar to that established for hepatitis C virus (HCV). The selection marker and reporter (Luc-Ubi-Neo) in the BVDV replicon was fused with the amino-terminal proteas...

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Detalhes bibliográficos
Main Authors: Horscroft, Nigel, Bellows, Dan, Ansari, Israrul, Lai, Vicky C. H., Dempsey, Shannon, Liang, Delin, Donis, Ruben, Zhong, Weidong, Hong, Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC548457/
https://ncbi.nlm.nih.gov/pubmed/15708997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.5.2788-2796.2005
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