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Platelet-activating factor causes ventilation-perfusion mismatch in humans.

We hypothesized that platelet-activating factor (PAF), a potent inflammatory mediator, could induce gas exchange abnormalities in normal humans. To this end, the effect of aerosolized PAF (2 mg/ml solution; 24 micrograms) on ventilation-perfusion (VA/Q) relationships, hemodynamics, and resistance of...

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書誌詳細
出版年:J Clin Invest
主要な著者: Rodriguez-Roisin, R, Félez, M A, Chung, K F, Barberà, J A, Wagner, P D, Cobos, A, Barnes, P J, Roca, J
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 1994
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC293752/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8282786/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116944
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