Platelet-activating factor causes ventilation-perfusion mismatch in humans.

We hypothesized that platelet-activating factor (PAF), a potent inflammatory mediator, could induce gas exchange abnormalities in normal humans. To this end, the effect of aerosolized PAF (2 mg/ml solution; 24 micrograms) on ventilation-perfusion (VA/Q) relationships, hemodynamics, and resistance of...

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Pubblicato in:	J Clin Invest
Autori principali:	Rodriguez-Roisin, R, Félez, M A, Chung, K F, Barberà, J A, Wagner, P D, Cobos, A, Barnes, P J, Roca, J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC293752/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8282786/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116944
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