Platelet-activating factor causes ventilation-perfusion mismatch in humans.

We hypothesized that platelet-activating factor (PAF), a potent inflammatory mediator, could induce gas exchange abnormalities in normal humans. To this end, the effect of aerosolized PAF (2 mg/ml solution; 24 micrograms) on ventilation-perfusion (VA/Q) relationships, hemodynamics, and resistance of...

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Detalhes bibliográficos
Main Authors: Rodriguez-Roisin, R, Félez, M A, Chung, K F, Barberà, J A, Wagner, P D, Cobos, A, Barnes, P J, Roca, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC293752/
https://ncbi.nlm.nih.gov/pubmed/8282786
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