Frameshift Mutations in a Single Novel Virulence Factor Alter the In Vivo Pathogenicity of Chlamydia trachomatis for the Female Murine Genital Tract

Chlamydia trachomatis is a human pathogen of global importance. An obstacle to studying the pathophysiology of human chlamydial disease is the lack of a suitable murine model of C. trachomatis infection. Mice are less susceptible to infection with human isolates due in part to innate mouse-specific...

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Autori principali: Sturdevant, Gail L., Kari, Laszlo, Gardner, Donald J., Olivares-Zavaleta, Norma, Randall, Linnell B., Whitmire, William M., Carlson, John H., Goheen, Morgan M., Selleck, Elizabeth M., Martens, Craig, Caldwell, Harlan D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
Soggetti:
Molecular Pathogenesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937465/
https://ncbi.nlm.nih.gov/pubmed/20547745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00386-10
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