Inhibition of endotoxin-induced activation of coagulation and fibrinolysis by pentoxifylline or by a monoclonal anti-tissue factor antibody in chimpanzees.

Knowledge of the pathogenetic mechanisms responsible for the activation of the coagulation system associated with endotoxemia is important for the development of improved modalities for prevention and treatment. We analyzed the appearance in plasma of TNF, IL-6, and indices of coagulation and fibrin...

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Detalhes bibliográficos
Main Authors: Levi, M, ten Cate, H, Bauer, K A, van der Poll, T, Edgington, T S, Büller, H R, van Deventer, S J, Hack, C E, ten Cate, J W, Rosenberg, R D
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC293743/
https://ncbi.nlm.nih.gov/pubmed/8282778
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