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Activated Protein C Inhibits Local Coagulation after Intrapulmonary Delivery of Endotoxin in Humans

Rationale: Acute lung injury and pneumonia are associated with pulmonary activation of coagulation and suppression of fibrinolysis, resulting in fibrin deposition in the lung. Activated protein C (APC) has systemic anticoagulant effects in patients with sepsis. Objective: To determine the effect of...

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Main Authors: van der Poll, Tom, Levi, Marcel, Nick, Jerry A., Abraham, Edward
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718442/
https://ncbi.nlm.nih.gov/pubmed/15750041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200411-1483OC
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