Insulin-like Growth Factor–1 Levels Contribute to the Development of Bacterial Translocation in Sepsis

Rationale: Many lines of evidence point toward the gastrointestinal (GI) tract in the pathophysiology of organ dysfunction in sepsis. Splanchnic hypoperfusion during sepsis leads to enterocyte apoptosis, diminished barrier function, and release of bacterial products. Sepsis lowers levels of insulin-...

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Main Authors: Hunninghake, Gary W., Doerschug, Kevin C., Nymon, Amanda B., Schmidt, Gregory A., Meyerholz, David K., Ashare, Alix
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2010
Teme:
D. Critical Care
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937242/
https://ncbi.nlm.nih.gov/pubmed/20413631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200911-1757OC
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