Insulin-like Growth Factor–1 Levels Contribute to the Development of Bacterial Translocation in Sepsis

Rationale: Many lines of evidence point toward the gastrointestinal (GI) tract in the pathophysiology of organ dysfunction in sepsis. Splanchnic hypoperfusion during sepsis leads to enterocyte apoptosis, diminished barrier function, and release of bacterial products. Sepsis lowers levels of insulin-...

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Hlavní autoři: Hunninghake, Gary W., Doerschug, Kevin C., Nymon, Amanda B., Schmidt, Gregory A., Meyerholz, David K., Ashare, Alix
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2010
Témata:
D. Critical Care
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937242/
https://ncbi.nlm.nih.gov/pubmed/20413631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200911-1757OC
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