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Human Airway Contraction and Formoterol-Induced Relaxation Is Determined by Ca(2+) Oscillations and Ca(2+) Sensitivity

The etiology of airway hyperresponsiveness associated with asthma requires an understanding of the regulatory mechanisms mediating human airway smooth muscle cell (SMC) contraction. The objective of this study was to determine how human airway SMC contraction (induced by histamine) and relaxation (i...

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Autors principals: Ressmeyer, Anna-Rebekka, Bai, Yan, Delmotte, Philippe, Uy, Karl F., Thistlethwaite, Patricia, Fraire, Armando, Sato, Osamu, Ikebe, Mitsuo, Sanderson, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937231/
https://ncbi.nlm.nih.gov/pubmed/19767449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0222OC
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