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Store‐operated calcium entry is required for sustained contraction and Ca(2+) oscillations of airway smooth muscle

KEY POINTS: Airway hyper‐responsiveness in asthma is driven by excessive contraction of airway smooth muscle cells (ASMCs). Agonist‐induced Ca(2+) oscillations underlie this contraction of ASMCs and the magnitude of this contraction is proportional to the Ca(2+) oscillation frequency. Sustained cont...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Chen, Jun, Sanderson, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430234/
https://ncbi.nlm.nih.gov/pubmed/27396568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272694
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