Steroid-resistant asthma. Cellular mechanisms contributing to inadequate response to glucocorticoid therapy.

The current study examined whether alterations in glucocorticoid receptor (GR) binding contribute to poor response to glucocorticoid therapy in asthma. 29 asthma patients with forced expiratory volume in 1 s (FEV1) < 70% predicted were studied. Patients were classified as steroid sensitive (SS) i...

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Detalhes bibliográficos
Main Authors: Sher, E R, Leung, D Y, Surs, W, Kam, J C, Zieg, G, Kamada, A K, Szefler, S J
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC293719/
https://ncbi.nlm.nih.gov/pubmed/8282803
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