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Rhabdomyosarcomas do not contain mutations in the DNA binding domains of myogenic transcription factors.

Skeletal myogenesis is regulated by a group of transcription factors (MyoD, myogenin, myf5, and myf6) that are "basic helix-loop-helix" proteins that bind to the promoters of muscle-specific genes and promote their expression. We have previously shown that after a mutation of Leu122 to Arg...

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Detalhes bibliográficos
Main Authors: Anand, G, Shapiro, D N, Dickman, P S, Prochownik, E V
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC293710/
https://ncbi.nlm.nih.gov/pubmed/8282820
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