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Protein- and DNA-Based Active Immunotherapy Targeting Interleukin-13 Receptor Alpha2

High-grade astrocytoma (HGA) is an invariably fatal malignancy with a mean survival of 14 months despite surgery, radiation, and chemotherapy. We have found that a restricted receptor for interleukin-13 (IL-13), IL-13 receptor alpha 2 (IL13Rα2), is abundantly overexpressed in the vast majority of HG...

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Autors principals: Mintz, Akiva, Gibo, Denise M., MadhanKumar, A.B., Cladel, Nancy M., Christensen, Neil D., Debinski, Waldemar
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936944/
https://ncbi.nlm.nih.gov/pubmed/18976118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2008.0462
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