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A second-generation vaccine protects against the psychoactive effects of cocaine

The effects of immunization with the second-generation cocaine immunoconjugate GND-keyhole limpet hemocyanin (KLH) or with the anti-cocaine mAb GNC92H2 were assessed in a model of acute cocaine-induced locomotor activity. After i.p. administration of cocaine⋅HCl (15 mg/kg), rats were tested in photo...

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Detalhes bibliográficos
Main Authors: Carrera, M. Rocío A., Ashley, Jon A., Wirsching, Peter, Koob, George F., Janda, Kim D.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC29369/
https://ncbi.nlm.nih.gov/pubmed/11172063
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