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Cocaine vaccines: Antibody protection against relapse in a rat model

The efficacy of active immunization with the cocaine immunogen GNC-keyhole limpet hemocyanin (KLH) in preventing cocaine self-administration reinstatement was assessed in rats. An animal model of relapse was used where rats were trained to self-administer cocaine, subjected to a period of extinction...

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Detalhes bibliográficos
Main Authors: Carrera, M. Rocío A., Ashley, Jon A., Zhou, Bin, Wirsching, Peter, Koob, George F., Janda, Kim D.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18582/
https://ncbi.nlm.nih.gov/pubmed/10823960
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