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Pericyte-specific expression of PDGF beta receptor in mouse models with normal and deficient PDGF beta receptor signaling

BACKGROUND: Pericytes are integral members of the neurovascular unit. Using mouse models lacking endothelial-secreted platelet derived growth factor-B (PDGF-B) or platelet derived growth factor receptor beta (PDGFRβ) on pericytes, it has been demonstrated that PDGF-B/PDGFRβ interactions mediate peri...

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Détails bibliographiques
Auteurs principaux: Winkler, Ethan A, Bell, Robert D, Zlokovic, Berislav V
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936891/
https://ncbi.nlm.nih.gov/pubmed/20738866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-32
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