14-Deoxyandrographolide desensitizes hepatocytes to tumour necrosis factor-alpha-induced apoptosis through calcium-dependent tumour necrosis factor receptor superfamily member 1A release via the NO/cGMP pathway

BACKGROUND AND PURPOSE: Andrographis paniculata (AP) has been found to display hepatoprotective effect, although the mechanism of action of the active compounds of AP in this context still remains unclear. Here, we evaluated the hepatoprotective efficacy of 14-deoxyandrographolide (14-DAG), a bioact...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Roy, DN, Mandal, S, Sen, G, Mukhopadhyay, S, Biswas, T
פורמט: Artigo
שפה:Inglês
יצא לאור: Blackwell Publishing Ltd 2010
נושאים:
Research Papers
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936852/
https://ncbi.nlm.nih.gov/pubmed/20649583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00836.x
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