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In rat renal fibroblasts, mycophenolic acid inhibits proliferation and production of the chemokine CCL2, stimulated by tumour necrosis factor-α

BACKGROUND AND PURPOSE: Renal fibroblasts play a pivotal role in the development of tubulointerstitial fibrosis, a condition highly predictive of progression towards end-stage renal disease. The present study investigated the anti-mitogenic and anti-inflammatory effects of an inhibitor of inosine mo...

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Detalhes bibliográficos
Main Authors: Chang, Hong-Wei, Wu, Vin-Cent, Wu, Kwan-Dun, Huang, Hong-Yu, Hsieh, Bor-Shen, Chen, Yung-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936834/
https://ncbi.nlm.nih.gov/pubmed/20649565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00837.x
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