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Interaction between the N- and C-Terminal Domains Modulates the Stability and Lipid Binding of Apolipoprotein A–I

The tertiary structure of human and mouse apolipoprotein A–I (apoA-I) are comprised of an N-terminal helix bundle and independently folded C-terminal domain. To define the possible intramolecular interaction between the N- and C-terminal domains, we examined the effects on protein stability and lipi...

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Main Authors: Koyama, Mao, Tanaka, Masafumi, Dhanasekaran, Padmaja, Lund-Katz, Sissel, Phillips, Michael C., Saito, Hiroyuki
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936823/
https://ncbi.nlm.nih.gov/pubmed/19239199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802317v
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