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Lipoprotein(a) accelerates atherosclerosis in uremic mice

Uremic patients have increased plasma lipoprotein(a) [Lp(a)] levels and elevated risk of cardiovascular disease. Lp(a) is a subfraction of LDL, where apolipoprotein(a) [apo(a)] is disulfide bound to apolipoprotein B-100 (apoB). Lp(a) binds oxidized phospholipids (OxPL), and uremia increases lipoprot...

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Detalhes bibliográficos
Main Authors: Pedersen, Tanja X., McCormick, Sally P., Tsimikas, Sotirios, Bro, Susanne, Nielsen, Lars B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936745/
https://ncbi.nlm.nih.gov/pubmed/20584868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M006742
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