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Tie2 in Tumor Endothelial Signaling and Survival: Implications for Antiangiogenic Therapy
Signaling through the Tie2 receptor on endothelial cells has been shown to play an important role in normal and pathologic vascular development. We generated K1735 murine melanoma tumor cells that inducibly express soluble Tie2 receptor (Tie2Ex) to study the effects of inhibiting Tie2 signaling on t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2936700/ https://ncbi.nlm.nih.gov/pubmed/19276184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-08-0215 |
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