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Low brain allopregnanolone levels mediate flattened circadian activity associated with memory impairments in aged rats
BACKGROUND: Sleep and cognitive impairments are two of the most prevalent neuropsychiatric disorders in the aged population. Age-related memory dysfunctions can result from alterations in sleep/wake circadian rhythm. However, the underlying mechanism of these alterations is unknown. Here, we demonst...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2936666/ https://ncbi.nlm.nih.gov/pubmed/20471631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.03.022 |
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