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Natural killer cells in NOD.NK1.1 mice acquire cytolytic function during viral infection and provide protection against cytomegalovirus

Resting natural killer (NK) cells in nonobese diabetic (NOD) mice have impaired immune functions compared with NK cells from other mouse strains. Here we investigated how NOD NK cells respond after mouse cytomegalovirus (MCMV) infection, using NOD mice congenic for the protective NK gene complex fro...

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Autors principals: Orr, Mark T., Beilke, Joshua N., Proekt, Irina, Lanier, Lewis L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936652/
https://ncbi.nlm.nih.gov/pubmed/20733071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010685107
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