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miRNA-based mechanism for the commitment of multipotent progenitors to a single cellular fate
When stem cells and multipotent progenitors differentiate, they undergo fate restriction, enabling a single fate and blocking differentiation along alternative routes. We herein present a mechanism whereby such unequivocal commitment is achieved, based on microRNA (miRNA)-dependent repression of an...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2936650/ https://ncbi.nlm.nih.gov/pubmed/20720163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0915022107 |
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