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Conserved microRNA targeting in Drosophila is as widespread in coding regions as in 3′UTRs

MicroRNAs (miRNAs) are a class of short noncoding RNAs that regulate protein-coding genes posttranscriptionally. In animals, most known miRNA targeting occurs within the 3′UTR of mRNAs, but the extent of biologically relevant targeting in the ORF or 5′UTR of mRNAs remains unknown. Here, we develop a...

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Detalhes bibliográficos
Main Authors: Schnall-Levin, Michael, Zhao, Yong, Perrimon, Norbert, Berger, Bonnie
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936641/
https://ncbi.nlm.nih.gov/pubmed/20729470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006172107
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