Leucine-rich repeat protein PRAME: expression, potential functions and clinical implications for leukaemia

PRAME/MAPE/OIP4 is a germinal tissue-specific gene that is also expressed at high levels in haematological malignancies and solid tumours. The physiological functions of PRAME in normal and tumour cells are unknown, although a role in the regulation of retinoic acid signalling has been proposed. Seq...

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Detalhes bibliográficos
Main Authors: Wadelin, Frances, Fulton, Joel, McEwan, Paul A, Spriggs, Keith A, Emsley, Jonas, Heery, David M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936344/
https://ncbi.nlm.nih.gov/pubmed/20799951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-226
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