Binding of platelet glycoprotein Ibβ through the convex surface of leucine-rich repeats domain of glycoprotein IX

BACKGROUND: The mechanism of assembly of the platelet glycoprotein (GP) Ib-IX complex from GPIbα, GPIbβ and GPIX subunits is not entirely clear. In this complex, ectodomains of both GPIbβ and GPIX subunits contain two leucine-rich repeats (LRR) and share high sequence similarity. However, they diffe...

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Auteurs principaux: Mo, Xi, Nguyen, Nam X., McEwan, Paul A., Zheng, Xiaofeng, López, José A., Emsley, Jonas, Li, Renhao
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046765/
https://ncbi.nlm.nih.gov/pubmed/19566547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2009.03536.x
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