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Gefitinib radiosensitizes non-small cell lung cancer cells through inhibition of ataxia telangiectasia mutated

PURPOSE: Inhibitors of epidermal growth factor receptor (EGFR) have shown dramatic results in a subset of patients with non-small cell lung cancer (NSCLC), and have also been shown to enhance the effect of ionizing radiation (IR). We investigated how gefitinib, an orally given EGFR inhibitor for NSC...

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Detalhes bibliográficos
Main Authors: Park, Soo-Yeon, Kim, Young Mee, Pyo, Hongryull
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936341/
https://ncbi.nlm.nih.gov/pubmed/20731837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-222
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