Regulatory T cell frequency in patients with melanoma with different disease stage and course, and modulating effects of high-dose interferon-α 2b treatment

BACKGROUND: High-dose interferon-alpha 2b (IFN-α 2b) is the only approved systemic therapy in the United States for the adjuvant treatment of melanoma. The study objective was to explore the immunomodulatory mechanism of action for IFN-α 2b by measuring serum regulatory T cell (Treg), serum transfor...

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Detalhes bibliográficos
Main Authors: Ascierto, Paolo A, Napolitano, Maria, Celentano, Egidio, Simeone, Ester, Gentilcore, Giusy, Daponte, Antonio, Capone, Mariaelena, Caracò, Corrado, Calemma, Rosa, Beneduce, Gerardo, Cerrone, Margherita, De Rosa, Vincenzo, Palmieri, Giuseppe, Castello, Giuseppe, Kirkwood, John M, Marincola, Francesco M, Mozzillo, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936304/
https://ncbi.nlm.nih.gov/pubmed/20712892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-8-76
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