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Endothelin signalling regulates volume-sensitive Cl(−) current via NADPH oxidase and mitochondrial reactive oxygen species
AIMS: We assessed regulation of volume-sensitive Cl(−) current (I(Cl,swell)) by endothelin-1 (ET-1) and characterized the signalling pathway responsible for its activation in rabbit atrial and ventricular myocytes. METHODS AND RESULTS: ET-1 elicited I(Cl,swell) under isosmotic conditions. Outwardly...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2936123/ https://ncbi.nlm.nih.gov/pubmed/20444986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq125 |
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