Riluzole protects against cardiac ischaemia and reperfusion damage via block of the persistent sodium current

BACKGROUND AND PURPOSE: Current strategies to ameliorate cardiac ischaemic and reperfusion damage, including block of the sodium-hydrogen exchanger, are therapeutically ineffective. Here we propose a different approach, block of the persistent sodium current (INaP). EXPERIMENTAL APPROACH: Left ventr...

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Detalhes bibliográficos
Main Authors: Weiss, S, Benoist, D, White, E, Teng, W, Saint, DA
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936017/
https://ncbi.nlm.nih.gov/pubmed/20590601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00766.x
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