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Tonic and use-dependent block of sodium currents in isolated cardiac myocytes by bisaramil.

1. The effects of bisaramil on sodium currents in rat isolated cardiac myocytes were examined by use of tight-seal, whole-cell patch clamp techniques. Bisaramil produced a concentration-dependent, readily reversible reduction in peak transient sodium current. When the sodium current was evoked at 3...

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Detalhes bibliográficos
Main Authors: Pugsley, M K, Saint, D A
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1510250/
https://ncbi.nlm.nih.gov/pubmed/7881737
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