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Mechanisms mediating the ability of caffeine to influence MDMA (‘Ecstasy’)-induced hyperthermia in rats

BACKGROUND AND PURPOSE: Caffeine exacerbates the hyperthermia associated with an acute exposure to 3,4 methylenedioxymethamphetamine (MDMA, ‘Ecstasy’) in rats. The present study investigated the mechanisms mediating this interaction. EXPERIMENTAL APPROACH: Adult male Sprague-Dawley rats were treated...

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Autors principals: Vanattou-Saïfoudine, N, McNamara, R, Harkin, A
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935994/
https://ncbi.nlm.nih.gov/pubmed/20590585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00660.x
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