N-Methyl-d-Aspartate Receptor and Neuronal Nitric Oxide Synthase Activation Mediate Bilirubin-Induced Neurotoxicity

Hyperbilirubinemia may lead to neurotoxicity and neuronal death. Although the mechanisms of nerve cell damage by unconjugated bilirubin (UCB) appear to involve a disruption of the redox status and excitotoxicity, the contribution of nitric oxide (NO·) and of N-methyl-d-aspartate (NMDA) glutamate rec...

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Main Authors: Brito, Maria A, Vaz, Ana R, Silva, Sandra L, Falcão, Ana S, Fernandes, Adelaide, Silva, Rui FM, Brites, Dora
Formato: Artigo
Idioma:Inglês
Publicado: ScholarOne 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935951/
https://ncbi.nlm.nih.gov/pubmed/20593111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2009.00152
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