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Mutant WDR36 directly affects axon growth of retinal ganglion cells leading to progressive retinal degeneration in mice

Primary open-angle glaucoma (POAG) is one of the three principal subtypes of glaucoma and among the leading cause of blindness worldwide. POAG is defined by cell death of the retinal ganglion cells (RGCs) and surrounding neuronal cells at higher or normal intraocular pressure (IOP). Coded by one of...

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Detalhes bibliográficos
Main Authors: Chi, Zai-Long, Yasumoto, Fumie, Sergeev, Yuri, Minami, Masayoshi, Obazawa, Minoru, Kimura, Itaru, Takada, Yuichiro, Iwata, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935858/
https://ncbi.nlm.nih.gov/pubmed/20631153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq299
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