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The heterogeneity of the kinetics of response to ipilimumab in metastatic melanoma: patient cases

Cytotoxic T lymphocyte antigen-4 (CTLA-4) is a negative regulator of T-cell mediated immune responses and is the target of new anti-tumor immunotherapy strategies. Ipilimumab is a fully human, antagonistic monoclonal antibody directed against CTLA-4. Results from preclinical and early clinical trial...

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Detalhes bibliográficos
Main Authors: Saenger, Yvonne M., Wolchok, Jedd D.
Formato: Artigo
Idioma:Inglês
Publicado em: Academy of Cancer Immunology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935787/
https://ncbi.nlm.nih.gov/pubmed/18198818
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