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Blockade of GITR–GITRL interaction maintains Treg function to prolong allograft survival
Involvement of Treg in transplant tolerance has been demonstrated in multiple models. During the active process of graft rejection, these regulatory cells are themselves regulated and inactivated, a process termed counter-regulation. We hypothesize that ligation of the costimulatory molecule glucoco...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2935584/ https://ncbi.nlm.nih.gov/pubmed/20148423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200940046 |
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