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GITR blockade facilitates T-reg mediated allograft survival
BACKGROUND: Many models of transplant tolerance have been found to depend upon the induction of regulatory T cells (T-regs). Innate immune signals are known to down-regulate T-regs thereby augmenting immunity by abrogating regulatory T cell function. Such signals may also provide a barrier to transp...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2803064/ https://ncbi.nlm.nih.gov/pubmed/19935370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3181ba6f85 |
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