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Improving disease gene prioritization using the semantic similarity of Gene Ontology terms
Motivation: Many hereditary human diseases are polygenic, resulting from sequence alterations in multiple genes. Genomic linkage and association studies are commonly performed for identifying disease-related genes. Such studies often yield lists of up to several hundred candidate genes, which have t...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2935448/ https://ncbi.nlm.nih.gov/pubmed/20823322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq384 |
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