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Dynamic deterministic effects propagation networks: learning signalling pathways from longitudinal protein array data

Motivation: Network modelling in systems biology has become an important tool to study molecular interactions in cancer research, because understanding the interplay of proteins is necessary for developing novel drugs and therapies. De novo reconstruction of signalling pathways from data allows to u...

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Detalhes bibliográficos
Main Authors: Bender, Christian, Henjes, Frauke, Fröhlich, Holger, Wiemann, Stefan, Korf, Ulrike, Beißbarth, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935402/
https://ncbi.nlm.nih.gov/pubmed/20823327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq385
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