Decreased Levels of Bisecting GlcNAc Glycoforms of IgG Are Associated with Human Longevity

BACKGROUND: Markers for longevity that reflect the health condition and predict healthy aging are extremely scarce. Such markers are, however, valuable in aging research. It has been shown previously that the N-glycosylation pattern of human immunoglobulin G (IgG) is age-dependent. Here we investiga...

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Detalhes bibliográficos
Main Authors: Ruhaak, L. Renee, Uh, Hae-Won, Beekman, Marian, Koeleman, Carolien A. M., Hokke, Cornelis H., Westendorp, Rudi G. J., Wuhrer, Manfred, Houwing-Duistermaat, Jeanine J., Slagboom, P. Eline, Deelder, André M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935362/
https://ncbi.nlm.nih.gov/pubmed/20830288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012566
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