Genetic Alterations in the Phosphatidylinositol-3 Kinase/Akt Pathway in Thyroid Cancer

BACKGROUND: Aberrant activation of the phosphatidylinositol-3 kinase (PI3K)/Akt pathway plays a fundamental role in thyroid tumorigenesis, particularly in follicular thyroid cancer (FTC) and aggressive thyroid cancer, such as anaplastic thyroid cancer (ATC). As the drivers of this process, many gene...

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Detalhes bibliográficos
Autor principal: Xing, Mingzhao
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Original Studies, Reviews, and Scholarly Dialog Special Section: Thyroid Disease in the Era of Personalized Medicine Guest Editors: Yaron Tomer, Virginia Sarapura, and George J. Kahaly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935335/
https://ncbi.nlm.nih.gov/pubmed/20578891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2010.1646
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