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High-Level Azithromycin Resistance Occurs in Neisseria gonorrhoeae as a Result of a Single Point Mutation in the 23S rRNA Genes

High-level azithromycin resistance (AZM-HR), defined as a MIC of ≥256 mg/liter, emerged in Neisseria gonorrhoeae in the United Kingdom in 2004. To determine the mechanism of this novel phenotype, isolates from the United Kingdom that were AZM-HR (n, 19), moderately AZM resistant (MICs, 2 to 8 mg/lit...

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書誌詳細
主要な著者: Chisholm, Stephanie A., Dave, Jayshree, Ison, Catherine A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935028/
https://ncbi.nlm.nih.gov/pubmed/20585125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00309-10
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