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Investigations into the Role of the Plasmodium falciparum SERCA (PfATP6) L263E Mutation in Artemisinin Action and Resistance

Artemisinin-based combination therapies (ACTs) are highly effective for the treatment of Plasmodium falciparum malaria, yet their sustained efficacy is threatened by the potential spread of parasite resistance. Recent studies have provided evidence that artemisinins can inhibit the function of PfATP...

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Autors principals: Valderramos, Stephanie Gaw, Scanfeld, Daniel, Uhlemann, Anne-Catrin, Fidock, David A., Krishna, Sanjeev
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935017/
https://ncbi.nlm.nih.gov/pubmed/20566762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00121-10
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